Successful clinical study for an innovative dengue vaccine, supervised by UNIL professor – News – CIVIS – Europe’s Civic University Alliance [Μετάβαση στο περιεχόμενο](#main) ![](https://civis.eu/build/assets/circle-03-DvaxLIQk.svg) ![](https://civis.eu/build/assets/circle-04-D4E6Ss3k.svg) ![](https://civis.eu/build/assets/circle-06-H_YyMKlQ.svg) [ ![CIVIS – Europe’s Civic University Alliance](https://civis.eu/build/assets/civis-CCpvK1nT.svg)](https://civis.eu/el) - [ Ανακάλυψε ](https://civis.eu/el/discover-civis-alliance) - [ Τι είναι το CIVIS; ](https://civis.eu/el/discover-civis-alliance/what-is-civis) - [ Το έργο μας ](https://civis.eu/el/discover-civis-alliance/our-work) - [ Αποστολή, Όραμα & Αξίες ](https://civis.eu/el/discover-civis-alliance/our-institutional-journey) - [ Διακυβέρνηση & Διαχείριση ](https://civis.eu/el/discover-civis-alliance/governance-andamp-management) - [ Ποιος είναι Ποιος ](https://civis.eu/el/discover-civis-alliance/who-is-who) - [ CIVIS Association ](https://civis.eu/el/discover-civis-alliance/civis-association) [Ανοιχτά εργαστήρια & Συμμετοχή των πολιτών ](https://civis.eu/el/discover-civis-alliance/our-work/open-labs-civic-engagement) - [ Σπούδασε ](https://civis.eu/el/learn) - [ Μικτά Εντατικά προγράμματα ](https://civis.eu/el/learn/blended-intensive-programmes) - [ Ευέλικτη μάθηση ](https://civis.eu/el/learn/build-your-learning-path-with-our-modular-offer) - [ Μεταπτυχιακά προγράμματα ](https://civis.eu/el/learn/find-your-master-s-programme) - [ Εβδομάδες Κατάρτισης Προσωπικού & Παρακολούθηση Εργασίας ](https://civis.eu/el/learn/keep-on-learning-with-staff-weeks-andamp-job-shadowing) - [ Σπούδασε στο εξωτερικό ](https://civis.eu/el/learn/study-abroad-and-connect-with-civis-universities) [Discover the projects led by our students in 2025-2026 ](https://civis.eu/el/discover-civis-alliance/our-work/student-led-projects/discover-the-projects-led-by-our-students-in-2025-2026) [Μουσείο CIVIS Φόρουμ Πανεπιστημίων ](https://civis.eu/el/discover-civis-alliance/our-work/CIVIS-Museum-University-Forum) - [ Δίδαξε ](https://civis.eu/el/teach) - [ Προσκλήσεις υποβολής προτάσεων έργων ](https://civis.eu/el/teach/civis-calls) - [ Καινοτομήστε στη διδασκαλία σας ](https://civis.eu/el/teach/innovate-your-teaching) - [ Πόροι για εκπαιδευτικούς ](https://civis.eu/el/teach/resources-for-educators) [Μικτά Εντατικά Προγράμματα CIVIS: Ισχυρός Αντίκτυπος και Υψηλά Ποσοστά Ικανοποίησης, σύμφωνα με Νέα Έκθεση ](https://civis.eu/el/the-civis-newsroom/civis-bips-strong-impact-and-high-satisfaction-new-report-finds) [Όταν η Τέχνη Υπερβαίνει τους Τίτλους των Ειδήσεων: Το CIVIS Open Lab Επαναδιεκδικεί την Έννοια του Σπιτιού ](https://civis.eu/el/the-civis-newsroom/when-art-speaks-louder-than-headlines-civis-open-lab-reclaims-the-meaning-of-home) - [ Κάνε έρευνα ](https://civis.eu/el/research) - [ Συνεργασία στην έρευνα ](https://civis.eu/el/research/research-collaboration) - [ Σταδιοδρομία, Δίκτυα & Κινητικότητα ](https://civis.eu/el/research/research-careers-networks-and-projects) - [ Πόροι για ερευνητές ](https://civis.eu/el/research/resources-for-researchers) [Είμαι ακαδημαϊκός/ερευνητής/-τρια ](https://civis.eu/el/i-am-an-academic-researcher) [Αντιμέτωποι με Κοινές Προκλήσεις, Διαμορφώνοντας Κοινές Λύσεις για την Αφρική και την Ευρώπη ](https://civis.eu/el/the-civis-newsroom/facing-common-challenges-shaping-joint-solutions-for-africa-and-europe) - [ Συνδέσου ](https://civis.eu/el/connect) - [ Ενημερωτικά Δελτία ](https://civis.eu/el/connect/newsletters) - [ Ημέρες CIVIS ](https://civis.eu/el/connect/civis-days) - [ Κοινωνία των Πολιτών ](https://civis.eu/el/discover-civis-alliance/our-work/open-labs-civic-engagement) - [ Επικοινωνήστε μαζί μας ](https://civis.eu/el/contact) - [ Τύπος και Επωνυμία ](https://civis.eu/el/connect/press-corner-branding-toolkit) [Ποιος είναι Ποιος ](https://civis.eu/el/discover-civis-alliance/who-is-who) [Fake It Till You News It: Challenges and Solutions in Modern Media Student Innovation Forum ](https://civis.eu/el/discover-civis-alliance/our-work/student-led-projects/discover-the-projects-led-by-our-students-in-2025-2026/civis-creathon-contest) [ Ιστορίες ](https://civis.eu/el/the-civis-newsroom) el - [ en ](https://civis.eu/en/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) - [ de ](https://civis.eu/de/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) - [ fr ](https://civis.eu/fr/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) - [ it ](https://civis.eu/it/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) - [ es ](https://civis.eu/es/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) - [ sv ](https://civis.eu/sv/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) - [ ro ](https://civis.eu/ro/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) Menu - [Ανακάλυψε](https://civis.eu/el/discover-civis-alliance) [ Toggle submenu ](#primary-nav-sm-collapse-29) - [ Τι είναι το CIVIS; ](https://civis.eu/el/discover-civis-alliance/what-is-civis) - [ Το έργο μας ](https://civis.eu/el/discover-civis-alliance/our-work) - [ Αποστολή, Όραμα & Αξίες ](https://civis.eu/el/discover-civis-alliance/our-institutional-journey) - [ Διακυβέρνηση & Διαχείριση ](https://civis.eu/el/discover-civis-alliance/governance-andamp-management) - [ Ποιος είναι Ποιος ](https://civis.eu/el/discover-civis-alliance/who-is-who) - [ CIVIS Association ](https://civis.eu/el/discover-civis-alliance/civis-association) - [Σπούδασε](https://civis.eu/el/learn) [ Toggle submenu ](#primary-nav-sm-collapse-30) - [ Μικτά Εντατικά προγράμματα ](https://civis.eu/el/learn/blended-intensive-programmes) - [ Ευέλικτη μάθηση ](https://civis.eu/el/learn/build-your-learning-path-with-our-modular-offer) - [ Μεταπτυχιακά προγράμματα ](https://civis.eu/el/learn/find-your-master-s-programme) - [ Εβδομάδες Κατάρτισης Προσωπικού & Παρακολούθηση Εργασίας ](https://civis.eu/el/learn/keep-on-learning-with-staff-weeks-andamp-job-shadowing) - [ Σπούδασε στο εξωτερικό ](https://civis.eu/el/learn/study-abroad-and-connect-with-civis-universities) - [Δίδαξε](https://civis.eu/el/teach) [ Toggle submenu ](#primary-nav-sm-collapse-31) - [ Προσκλήσεις υποβολής προτάσεων έργων ](https://civis.eu/el/teach/civis-calls) - [ Καινοτομήστε στη διδασκαλία σας ](https://civis.eu/el/teach/innovate-your-teaching) - [ Πόροι για εκπαιδευτικούς ](https://civis.eu/el/teach/resources-for-educators) - [Κάνε έρευνα](https://civis.eu/el/research) [ Toggle submenu ](#primary-nav-sm-collapse-32) - [ Συνεργασία στην έρευνα ](https://civis.eu/el/research/research-collaboration) - [ Σταδιοδρομία, Δίκτυα & Κινητικότητα ](https://civis.eu/el/research/research-careers-networks-and-projects) - [ Πόροι για ερευνητές ](https://civis.eu/el/research/resources-for-researchers) - [Συνδέσου](https://civis.eu/el/connect) [ Toggle submenu ](#primary-nav-sm-collapse-33) - [ Ενημερωτικά Δελτία ](https://civis.eu/el/connect/newsletters) - [ Ημέρες CIVIS ](https://civis.eu/el/connect/civis-days) - [ Κοινωνία των Πολιτών ](https://civis.eu/el/discover-civis-alliance/our-work/open-labs-civic-engagement) - [ Επικοινωνήστε μαζί μας ](https://civis.eu/el/contact) - [ Τύπος και Επωνυμία ](https://civis.eu/el/connect/press-corner-branding-toolkit) [ Ιστορίες ](https://civis.eu/el/the-civis-newsroom) el - [ en ](https://civis.eu/en/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) - [ de ](https://civis.eu/de/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) - [ fr ](https://civis.eu/fr/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) - [ it ](https://civis.eu/it/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) - [ es ](https://civis.eu/es/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) - [ sv ](https://civis.eu/sv/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) - [ ro ](https://civis.eu/ro/the-civis-newsroom/successful-clinical-study-for-an-innovative-dengue-vaccine-supervised-by-unil-s-professor) 1. [The CIVIS Newsroom ](https://civis.eu/el/the-civis-newsroom) 2. Successful clinical study for an innovative dengue vaccine, supervised by UNIL professor Successful clinical study for an innovative dengue vaccine, supervised by UNIL professor ========================================================================================== CIVIS Highlights 16 Φεβρουαρίου 2024 A new type of vaccine that induces cellular immunity to combat dengue fever has been the subject of a clinical study conducted by [Unisanté](https://www.unisante.ch/fr). The results, supervised by a professor from CIVIS member University UNIL, have just been published in the journal "*The Lancet eBioMedicine*" and encourage further investigation. This approach is also promising for other diseases. ![](/storage/files/header-stm-2022_2.png) stock photo by Canva​​​​​ A global health priority ------------------------ Global warming and urbanisation are facilitating the spread of the tiger mosquito, responsible for dengue fever. The World Health Oorganisation (WHO) estimates that almost half the world's population now lives in high-risk areas. Cases of dengue fever have increased eightfold in 20 years, leading to one hospitalisation per minute and two deaths per hour. Having **an effective vaccine is therefore a priority for global health**. Two dengue vaccines are currently available in Europe, but they are unsatisfactory in terms of safety and efficacy. Their technology is based on the production of antibodies which, in certain cases, can increase the severity of the disease when infected by the natural virus. Unisanté has evaluated the safety and immune response of a potential dengue vaccine (*PepGNP Dengue*), designed using an innovative technology to induce cellular immunity without stimulating antibody production. New approach and nano-innovations --------------------------------- The tested vaccine, PepGNP-Dengue, was developed in the UK by Emergex Vaccines. It consists of a nanodose of synthetic fragments of the virus fused to gold nanoparticles. Another special feature is that it is administered under the skin using a micro-needle. The vaccine relies on T lymphocytes, which are responsible for cellular immunity, to eliminate cells infected by the virus and prevent it from replicating. Emergex Vaccines chose Unisanté to carry out the clinical study in order to assess the safety of this vaccine, which is being administered to humans for the first time, given the institution's accumulated experience in evaluating vaccine candidates against Ebola and malaria in particular. The aim of phase 1 was to determine whether the vaccine did not induce severe undesirable side-effects in non-diseased volunteers. A total of 26 participants aged between 18 and 45 were vaccinated in Lausanne in 2021, and were followed for six months until March 2022. The results of this clinical study, supervised by Blaise Genton, Honorary Professor at UNIL, and coordinated by Dr Alix Miauton, Research Fellow at Unisanté, were published in January 2024 in The Lancet eBioMedicine. Positive results without adverse effects ---------------------------------------- During the trial, no serious adverse events related to the vaccine occurred. Local side effects (such as pain at the injection site) were the most frequently reported. Immunological results indicate that PepGNP-Dengue can stimulate a specific cellular response against the dengue virus without producing antibodies. These findings encourage further investigation into this innovative vaccine candidate and hold promise for other diseases where cellular immunity is important. A potential COVID-19 vaccine based on the same technology has also been tested by Unisanté on 26 participants, with results currently being published. **Dig into the [original story](https://news.unil.ch/display/1706104853462), in French.** Related news ------------ - [ ![](https://civis.eu/storage/files/unil-march-800x600.jpg?token=d8f751c5dd64924dd2e37edbb187d325)The Swiss ski mountaineering team, supported by UNIL's researchers for this year's Olympic Games CIVIS Highlights 3 Μαρτίου 2026 ](https://civis.eu/el/the-civis-newsroom/the-swiss-ski-mountaineering-team-supported-by-unil-s-researchers-for-this-year-s-olympic-games) - [ ![](https://civis.eu/storage/files/post-it-risks-800x600.jpg?token=3f32ba7f3ab0220e88eeac41defdd8bf)Innovative micro-credential for professionals on AI for the workplace launched by CIVIS Learn 10 Φεβρουαρίου 2026 ](https://civis.eu/el/the-civis-newsroom/civis-micro-credentials-ai-and-work-supporting-teams-through-change) - [ ![](https://civis.eu/storage/files/img-4583-800x600.jpg?token=9b1616d14128b09af2bc51cc05d57631)UNIL empowers master’s students to co-create research with partners in the field abroad CIVIS Highlights 17 Οκτωβρίου 2025 ](https://civis.eu/el/the-civis-newsroom/unil-empowers-master-s-students-to-co-create-research-with-partners-in-the-field-abroad) [Ανακαλύψτε όλες μας τις ιστορίες](https://civis.eu/el/the-civis-newsroom) [ Mission Europe pour la Recherche: towards a one-stop shop for European research funding ](< https://civis.eu/el/the-civis-newsroom/towards-a-one-stop-shop-to-apply-for-european-funding-launch-of-the-mission-europe-pour-la-recherche >) [ Sustainable renovation of the Lubumbashi University Clinics proposed by ULB-UNILU students ](< https://civis.eu/el/the-civis-newsroom/ulb-unilu-student-microproject-a-sustainable-renovation-of-the-lubumbashi-university-clinics >) ![CIVIS – Europe’s Civic University Alliance](https://civis.eu/build/assets/civis-CCpvK1nT.svg) ------------------------------------------------------------------------------------------------- Europe’s Civic University Alliance ![Co-funded by the European Union](https://civis.eu/build/assets/co-funded-by-the-european-union-DSKLW1us.png)Views and opinions expressed do not necessarily reflect those of the European Union or the European Education and Culture Executive Agency (EACEA). Neither can be held responsible for them. ### Άνθρωποι - [ Φοιτητές-/τριες ](https://civis.eu/el/i-am-a-student) - [ Ακαδημαϊκοί και ερευνητές ](https://civis.eu/el/i-am-an-academic-researcher) - [ Διοικητικοί ](https://civis.eu/el/i-am-an-administrator) - [ Κοινωνία των πολιτών ](https://civis.eu/el/discover-civis-alliance/our-work/open-labs-civic-engagement) - [ Τύπος ](https://civis.eu/el/connect/press-corner-branding-toolkit) ### Χρήσιμοι σύνδεσμοι - [ Πόροι ](https://civis.eu/el/resources) - [ Πλατφόρμα CIVIS Agora ](https://civis.eu/el/civis-agora-the-operational-hub-of-the-civis-digital-campus) - [ Πρωτοβουλία των Ευρωπαϊκών Πανεπιστημίων ](https://civis.eu/el/european-universities-initiative) - [ Προηγούμενες εκδηλώσεις ](https://civis.eu/el/past-events) - [ Επικοινωνία ](https://civis.eu/el/contact) [Newsletters](https://civis.eu/el/connect/newsletters) ### Social networks - [ ![](https://civis.eu/storage/files/instagram.svg) Instagram ](https://www.instagram.com/civis.eu/) - [ ![](https://civis.eu/storage/files/linkedin.svg) LinkedIn ](https://www.linkedin.com/company/civis-eu) - [ ![](https://civis.eu/storage/files/facebook.svg) Facebook ](https://www.facebook.com/CIVISEuropeanUniversity/) - [ ![](https://civis.eu/storage/files/youtube.svg) YouTube ](https://www.youtube.com/channel/UCdCm0FfreX81BuNH-znlRGQ) © 2026 – CIVIS – All rights reserved - [ Cookie Policy ](https://civis.eu/el/cookie-policy) - [ Privacy policy ](https://civis.eu/el/privacy-policy) Website by [Typi Design](https://typi.be) • Design by [Atelier Milky](https://ateliermilky.com) [ ](#top) Search